ganoderma lucidum induces the expression of cd40/cd86 on peripheral blood monocytes

Ganoderma Lucidum Induces the Expression of CD40/CD86 on Peripheral Blood Monocytes

Background: The major immuno-modulating effects of Ganoderma lucidum include mitogenicity and activation of immune effector cells such as T cells, macrophages and natural killer cells resulting in the production of cytokines. Objective: The purpose of this study was to evaluate the expression of CD40 and CD80 by G. lucidum-treated human peripheral blood mononuclear cells. Methods: Monocytes wer...

Ganoderma lucidum

Effect of Ganoderma Lucidum on Cytokine Release by Peritoneal Macrophages

Background: The water-soluble extract of Ganoderma lucidum (Reishi) has been used as an immunomodulator to stimulate spleen cells proliferation and cytokine expression. Objective: To investigate the effect of Ganoderma lucidum (G. lucidum) on cytokine production by mice peritoneal macrophages. Methods: Mice peritoneal macrophages were prepared by intra-peritoneal injection of 5 ml cold PBS. Per...

Molecular identification of Ganoderma lucidum from Iran

Medicinal mushroom Ganoderma lucidum has been used in East Asia for centuries in order to prevent and treat a variety of diseases such as hepatitis, immunological disorders and cancers. In fact, this fungus contains a vast source of polysaccharides, proteins and secondary metabolites with anti-tumor and immuno-modulatory properties. Up to now, a variety of drug metabolites extracted from G. luc...

The Innovation Research on the Extraction Technology of Ganoderma Lucidum

China is the birthplace of the Chinese Medicine. Ganoderma lucidum as a traditional Chinese treasure with Millenium history of medicinal herbs, its medical and health care functions have come to be known to the general public. With the development of technology, G. lucidum health food ceaseless emerges in large numbers. But G. lucidum health food differs in efficacy, component, and content; hea...

Interleukin-1 induces interleukin-6 production in peripheral blood monocytes.

Interleukin-6 (IL-6), a multifunctional cytokine produced in monocytes, fibroblasts, endothelial cells, and keratinocytes, is induced by a variety of stimulating signals, including lipopolysaccharide (LPS), poly (I), poly (C), IL-1, tumor necrosis factor (TNF), and platelet-derived growth factor. Some of these signals induce IL-6 effectively only in one cell type, and this selectivity of induct...